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Prenatal Carotenoid Supplementation With Lutein or Zeaxanthin Ameliorates Oxygen-Induced Retinopathy (OIR) in Bco2−/− Macular Pigment Mice

10 Apr 2023

Abstract excerpt

Purpose: Premature infants at risk of retinopathy of prematurity (ROP) miss placental transfer of the carotenoids lutein (L) and zeaxanthin (Z) during the third trimester. We previously demonstrated that prenatal L and Z supplementation raised carotenoid levels in infants at birth in the Lutein and Zeaxanthin in Pregnancy (L-ZIP) study (NCT03750968). Based on their antioxidant effects and bioavailability, we...

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PMID: 37036416
DOI: 10.1167/iovs.64.4.9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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