Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Zika virus has oncolytic activity against glioblastoma stem cells

5 Sept 2017

Abstract excerpt

Glioblastoma is a highly lethal brain cancer that frequently recurs in proximity to the original resection cavity. We explored the use of oncolytic virus therapy against glioblastoma with Zika virus (ZIKV), a flavivirus that induces cell death and differentiation of neural precursor cells in the developing fetus. ZIKV preferentially infected and killed glioblastoma stem cells (GSCs) relative to differentiated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Mosquito-borne diseases and control
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28874392
DOI: 10.1084/jem.20171093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Zika virus has oncolytic activity against glioblastoma stem cellsPMID 28874392Read ↗

Zika Virus: A New Therapeutic Candidate for Glioblastoma TreatmentSemantic proximity Read ↗

Oncolytic herpes simplex viruses for the treatment of glioma and targeting glioblastoma stem-like cellsSemantic proximity Read ↗

Transcriptomic Meta-Analysis and Functional Validation Identify a Long Non-Coding RNA Network That Governs Zika Virus Oncolysis in Glioblastoma MultiformeSemantic proximity Read ↗

Restriction of Replication of Oncolytic Herpes Simplex Virus with a Deletion of γ34.5 in Glioblastoma Stem-Like CellsSemantic proximity Read ↗

Genetically modified ZIKA virus as a microRNA-sensitive oncolytic virus against central nervous system tumorsSemantic proximity Read ↗

Oncolytic Virus Therapy for Glioblastoma MultiformeSemantic proximity Read ↗

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 AxisSemantic proximity Read ↗

Strategies in Gene Therapy for GlioblastomaSemantic proximity Read ↗

Zika Virus with Increased CpG Dinucleotide Frequencies Shows Oncolytic Activity in Glioblastoma Stem CellsSemantic proximity Read ↗

Zika Virus Neuropathogenesis—Research and UnderstandingSemantic proximity Read ↗

Zika virus infection dysregulates human neural stem cell growth and inhibits differentiation into neuroprogenitor cellsSemantic proximity Read ↗

Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.