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Article

Synergistic Association of Genetic Variants with Environmental Risk Factors in Susceptibility to Essential Hypertension.

Genetic testing and molecular biomarkers - 1 Oct 2017

Sousa Ana Célia, Mendonça Maria I, Pereira Andreia, Gouveia Sara, Freitas Ana I, Guerra Graça, Rodrigues Mariana, Henriques Eva, Freitas Sónia, Borges Sofia, Pereira Décio, Brehm António, Palma Dos Reis Roberto

Abstract excerpt

AIMS: Essential hypertension (EH) is a disease in which both environment and genes have an important role. This study was designed to identify the interaction model between genetic variants and environmental risk factors that most highly potentiates EH development. METHODS: We performed a case-control study with 1641 participants (mean age 50.6 ± 8.1 years), specifically 848 patients with EH and 793 controls,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28872890
DOI: 10.1089/gtmb.2017.0048

Genes

ADD1

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