Article
Ancestry & molecular evolutionary analyses of heat shock protein 47 kDa (HSP47/SERPINH1).
Scientific reports - 4 Sept 2017
Kumar Abhishek, Bhandari Anita, Sarde Sandeep J, Goswami Chandan
Abstract excerpt
HSP47/SERPINH1 is key-regulator for collagen biosynthesis and its structural assembly. To date, there is no comprehensive study on the phylogenetic history of HSP47. Herein we illustrate the evolutionary history of HSP47/SERPINH1 along with sequence, structural and syntenic traits for HSP47/SERPINH1. We have identified ancestral HSP47/SERPINH1 locus in Japanese lamprey (Lethenteron japonicum). This gene remains...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
