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Article

Identification of HSP90 inhibitors as a novel class of senolytics

29 Aug 2017

Abstract excerpt

Abstract Aging is the main risk factor for many chronic degenerative diseases and cancer. Increased senescent cell burden in various tissues is a major contributor to aging and age-related diseases. Recently, a new class of drugs termed senolytics were demonstrated to extending healthspan, reducing frailty and improving stem cell function in multiple murine models of aging. To identify novel and more optimal...

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Share to Circadian rhythm and melatonin
Share to Genetics, Aging, and Longevity in Model Organisms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28871086
DOI: 10.1038/s41467-017-00314-z

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