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Article

Characterization of the HDAC/PI3K inhibitor CUDC-907 as a novel senolytic

28 Mar 2023

Abstract excerpt

The accumulation of senescent cells has an important role in the phenotypical changes observed in ageing and in many age-related pathologies. Thus, the strategies designed to prevent these effects, collectively known as senotherapies, have a strong clinical potential. Senolytics are a type of senotherapy aimed at specifically eliminating senescent cells from tissues. Several small molecule compounds with...

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Share to Epigenetics and DNA Methylation
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PMID: 36988504
DOI: 10.18632/aging.204616

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