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Article

Association Between RASSF1A Promoter Methylation and Testicular Germ Cell Tumor: A Meta-analysis and a Cohort Study.

Cancer genomics & proteomics - 1 Jan 2000

Markulin Dora, Vojta Aleksandar, Samaržija Ivana, Gamulin Marija, Bečeheli Ivona, Jukić Irena, Maglov Čedomir, Zoldoš Vlatka, Fučić Aleksandra

Abstract excerpt

BACKGROUND: The RAS association domain family protein 1a (RASSF1A) is a prominent tumor suppressor gene showing altered promoter methylation in testicular germ cell tumors (TGCT). RASSF1A promoter hypermethylation might represent an early event in TGCT tumorigenesis. We investigated whether the RASSF1A promoter methylation in peripheral blood of TGCT patients can be associated with testicular cancer risk....

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Source

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Identifiers

PMID: 28871003
DOI: 10.21873/cgp.20046
PMCID: PMC5611522

Genes

MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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