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Article

The association between RASSF1A promoter methylation and prostate cancer: evidence from 19 published studies.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2014

Ge Yu-Zheng, Xu Lu-Wei, Jia Rui-Peng, Xu Zheng, Feng Yu-Ming, Wu Ran, Yu Peng, Zhao Yan, Gui Zan-Long, Tan Si-Jia, Song Qun

Abstract excerpt

Ras-associated domain family 1A (RASSF1A) is a putative tumor suppressor gene located at 3p21.3, and the epigenetic inactivation of RASSF1A by hypermethylation of CpG islands within the promoter region has been observed in various cancer types, including prostate cancer (PCa). However, results from published studies on the association between RASSF1A promoter methylation and PCa risk are conflicting and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24353088
DOI: 10.1007/s13277-013-1515-3

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