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Article

Multipoint methylation analysis indicates a distinctive epigenetic phenotype among testicular germ cell tumors and testicular malignant lymphomas.

Genes, chromosomes & cancer - 1 Sept 2003

Kawakami Takahiro, Okamoto Keisei, Kataoka Akira, Koizumi Shuichi, Iwaki Hideaki, Sugihara Hiroyuki, Reeve Anthony E, Ogawa Osamu, Okada Yusaku

Abstract excerpt

Hypermethylation of tumor-suppressor genes has been implicated in the pathogenesis of human cancers. Although a growing number of genes showing hypermethylation is being reported in human cancer, methylation profiles of tumor-related genes in testicular neoplasms have not been well elucidated. This study was designed to show the methylation profiles of multiple CpG islands in testicular germ cell tumors (TGCTs)...

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Topics

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Share to Cell Transformation, Neoplastic
Share to CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Gene Expression Regulation, Neoplastic

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Share to Testicular Neoplasms

Source

Identifiers

PMID: 12874790
DOI: 10.1002/gcc.10234

Genes

RARB
BRCA1
GSTP1
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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