Article
Exchange of terminal portions of X- and Y-chromosomal short arms in human XX males.
Nature - 1 Jan 2000
Page D C, Brown L G, de la Chapelle A
Abstract excerpt
In most human 'XX males', DNA sequences normally found on Yp, the short arm of the Y chromosome, are present on Xp, the short arm of the X chromosome. To establish whether this transfer involves a terminal portion of Yp, and whether a terminal portion of Xp is lost in the process, we followed the inheritance of pseudoautosomal restriction fragment length polymorphisms in two XX-male families. One XX male...
Topics
- Alleles
- DNA
- Humans
- Male
- Meiosis
- Phenotype
- Polymorphism, Restriction Fragment Length
- Recombination, Genetic
- Sex Chromosome Aberrations
- X Chromosome
- Y Chromosome