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Article

Genetic evidence that a Y-linked gene in man is homologous to a gene on the X chromosome.

Nature - 1 Jan 2000

Goodfellow P, Banting G, Sheer D, Ropers H H, Caine A, Ferguson-Smith M A, Povey S, Voss R

Abstract excerpt

The mammalian sex chromosomes are thought to be related to each other by sharing a common origin. That is, the X and Y chromosomes originally evolved from a pair of chromosomes that only differed at the locus determining sexual differentiation. For example, this evolutionary relationship is reflected during meiosis in chromosomal pairing between the tip of the human X chromosome short arm and the Y chromosome...

Topics

Alleles
Antibodies, Monoclonal
Antigens, Surface
Biological Evolution
Epitopes
Female
Genetic Linkage
Humans
Male
Polymorphism, Genetic
Sex Chromosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

X Chromosome

Y Chromosome

Source

Identifiers

PMID: 6188056
DOI: 10.1038/302346a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6188056-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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