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Article

Additional deletion in sex-determining region of human Y chromosome resolves paradox of X,t(Y;22) female.

Nature - 19 Jul 1990

Page D C, Fisher E M, McGillivray B, Brown L G

Abstract excerpt

Whether a human embryo develops as a male or a female is determined by the presence of the Y chromosome. The sex-determining function lies entirely in interval 1A, inasmuch as most XX individuals with descended testes and normal male external genitalia carry this small region of the Y chromosome. We have localized an essential part of the sex-determining function to a portion of interval 1A, on the basis of the...

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Share to Chromosome Deletion
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Sex Chromosome Aberrations

Share to Translocation, Genetic

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Source

Identifiers

PMID: 1973823
DOI: 10.1038/346279a0

Genes

ZFY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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