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Mitochondria-Associated Membranes As Networking Platforms and Regulators of Cancer Cell Fate

18 Aug 2017

Abstract excerpt

The tight cross talk between two essential organelles of the cell, the endoplasmic reticulum and mitochondria, is spatially and functionally regulated by specific microdomains known as the mitochondria-associated membranes or MAMs. MAMs are hot spots of Ca2+ transfer between the ER and mitochondria, and emerging data indicate their vital role in the regulation of fundamental physiological processes, chief among...

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PMID: 28868254
DOI: 10.3389/fonc.2017.00174

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