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Cellular senescence links mitochondria-ER contacts and aging

24 Nov 2021

Abstract excerpt

Membrane contact sites emerged in the last decade as key players in the integration, regulation and transmission of many signals within cells, with critical impact in multiple pathophysiological contexts. Numerous studies accordingly point to a role for mitochondria-endoplasmic reticulum contacts (MERCs) in modulating aging. Nonetheless, the driving cellular mechanisms behind this role remain unclear. Recent...

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PMID: 34819602
DOI: 10.1038/s42003-021-02840-5

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