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Article

Paneth Cell Defects Induce Microbiota Dysbiosis in Mice and Promote Visceral Hypersensitivity.

Gastroenterology - 1 Dec 2017

Riba Ambre, Olier Maïwenn, Lacroix-Lamandé Sonia, Lencina Corinne, Bacquié Valérie, Harkat Cherryl, Gillet Marion, Baron Marine, Sommer Caroline, Mallet Virginie, Salvador-Cartier Christel, Laurent Fabrice, Théodorou Vassilia, Ménard Sandrine

Abstract excerpt

BACKGROUND & AIMS: Separation of newborn rats from their mothers induces visceral hypersensitivity and impaired epithelial secretory cell lineages when they are adults. Little is known about the mechanisms by which maternal separation causes visceral hypersensitivity or its relationship with defects in epithelial secretory cell lineages. METHODS: We performed studies with C3H/HeN mice separated from their mothers...

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Identifiers

PMID: 28865734
DOI: 10.1053/j.gastro.2017.08.044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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