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Article

Susceptibility to stress induced visceral hypersensitivity in maternally separated rats is transferred across generations

21 Aug 2013

Abstract excerpt

BACKGROUND: In irritable bowel syndrome (IBS), familial clustering and transfer across generations may largely depend on environmental factors but this is difficult to establish in the human setting. Therefore, we aimed to set up a relevant animal model. We investigated whether susceptibility to stress induced visceral hypersensitivity in maternally separated (MS) Long Evans rats can be transferred across...

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PMID: 23965154
DOI: 10.1111/nmo.12202

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