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Article

Drosophila Nociceptive Sensitization Requires BMP Signaling via the Canonical SMAD Pathway

3 Aug 2017

Abstract excerpt

Nociceptive sensitization is a common feature in chronic pain, but its basic cellular mechanisms are only partially understood. The present study used the Drosophila melanogaster model system and a candidate gene approach to identify novel components required for modulation of an injury-induced nociceptive sensitization pathway presumably downstream of Hedgehog. This study demonstrates that RNAi silencing of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 28855331
DOI: 10.1523/jneurosci.3458-16.2017

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