Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes.

doi:10.1158/1541-7786.MCR-17-0134

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes.

Molecular cancer research : MCR - 1 Dec 2017

Zhang Li, MacIsaac Kenzie D, Zhou Ting, Huang Pei-Yu, Xin Chunlin, Dobson Jason R, Yu Kun, Chiang Derek Y, Fan Yue, Pelletier Marc, Wang Yan, Jaeger Savina, Krishnamurthy Radhakrishnan Viveksagar, JeBailey Lellean, Skewes-Cox Peter, Zhang Jing, Fang Wenfeng, Huang Yan, Zhao Hongyun, Zhao Yuanyuan, Li En, Peng Bin, Huang Alan, Dranoff Glenn, Hammerman Peter S, Engelman Jeffrey, Bitter Hans, Zeng Yi-Xin, Yao Yao

Abstract excerpt

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV) associated cancer characterized by a poor prognosis and a high level of lymphocyte infiltrate. Genetic hallmarks of NPC are not completely known but include deletion of the p16 (CDKN2A) locus and mutations in NF-κB pathway components, with a relatively low total mutational load. To better understand the genetic landscape, an integrated genomic analysis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p18

Share to Herpesvirus 4, Human

Share to Lymphocytes, Tumor-Infiltrating

Share to Nasopharyngeal Carcinoma

Share to Nasopharyngeal Neoplasms

Share to NF-kappa B

Share to Wnt Signaling Pathway

Source

Open in PubMed

Identifiers

PMID: 28851814
DOI: 10.1158/1541-7786.MCR-17-0134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes.PMID 28851814Read ↗

Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escapeSemantic proximity Read ↗

The genomic landscape of nasopharyngeal carcinoma.Semantic proximity Read ↗

Nasopharyngeal Cancer: Molecular Landscape.Semantic proximity Read ↗

Translational genomics of nasopharyngeal cancerSemantic proximity Read ↗

Genomic Landscapes of EBV-Associated Nasopharyngeal Carcinoma vs. HPV-Associated Head and Neck CancerSemantic proximity Read ↗

Epigenomic landscape study reveals molecular subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinomaSemantic proximity Read ↗

Comprehensive genomic profiling of different subtypes of nasopharyngeal carcinoma reveals similarities and differences to guide targeted therapy.Semantic proximity Read ↗

Genetic and epigenetic landscape of nasopharyngeal carcinoma.Semantic proximity Read ↗

Nasopharyngeal Carcinoma at the Virology Precision Oncology Nexus: Decoding Molecular Alterations for Early Intervention and Therapeutic Innovation.Semantic proximity Read ↗

Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations.Semantic proximity Read ↗

Nasopharyngeal carcinoma at the virology precision oncology nexus: decoding molecular alterations for early intervention and therapeutic innovationSemantic proximity Read ↗

Tumor immune microenvironment delineates progression trajectories of distinct nasopharyngeal carcinoma phenotypesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.