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Epigenomic landscape study reveals molecular subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

11 Nov 2022

Abstract excerpt

Background Epstein-Barr virus (EBV) latent infection is associated with genome-wide epigenomic changes in several malignancies, but its role in epigenetic dysregulation remains unclear in nasopharyngeal carcinoma (NPC). Methods To investigate EBV-associated epigenetic dysregulation, we performed a multi-omics study by integrating whole-genome bisulfite sequencing (WGBS), assay for transposase-accessible chromatin...

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Epigenetics and DNA Methylation
Head and Neck Cancer Studies
Viral-associated cancers and disorders

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36371985
DOI: 10.1016/j.ebiom.2022.104357

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