Article
Expression of pro-inflammatory cytokines in the auditory cortex of rats with salicylate-induced tinnitus.
Molecular medicine reports - 1 Oct 2017
Chen Xiang-Hong, Zheng Li-Li
Abstract excerpt
Tinnitus often results in severe psychological distress. The present study hypothesized that tinnitus acts as a chronic stressor and induces dysregulation of the production of cytokines. The gap pre‑pulse inhibition of acoustic startle paradigm was applied to test tinnitus‑like behavior in rats. Following this, the mRNA and protein expression levels of interferon (IFN)‑γ, tumor necrosis factor (TNF)‑α,...
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