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Article

Surveying the sequence diversity of model prebiotic peptides by mass spectrometry.

Proceedings of the National Academy of Sciences of the United States of America - 12 Sept 2017

Forsythe Jay G, Petrov Anton S, Millar W Calvin, Yu Sheng-Sheng, Krishnamurthy Ramanarayanan, Grover Martha A, Hud Nicholas V, Fernández Facundo M

Abstract excerpt

The rise of peptides with secondary structures and functions would have been a key step in the chemical evolution which led to life. As with modern biology, amino acid sequence would have been a primary determinant of peptide structure and activity in an origins-of-life scenario. It is a commonly held hypothesis that unique functional sequences would have emerged from a diverse soup of proto-peptides, yet there...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28847940
DOI: 10.1073/pnas.1711631114
PMCID: PMC5604043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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