Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High confidence prediction of essential genes in Burkholderia cenocepacia.

PloS one - 1 Jan 2012

Juhas Mario, Stark Manuel, von Mering Christian, Lumjiaktase Puthapoom, Crook Derrick W, Valvano Miguel A, Eberl Leo

Abstract excerpt

BACKGROUND: Essential genes are absolutely required for the survival of an organism. The identification of essential genes, besides being one of the most fundamental questions in biology, is also of interest for the emerging science of synthetic biology and for the development of novel antimicrobials. New antimicrobial therapies are desperately needed to treat multidrug-resistant pathogens, such as members of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Bacterial
Share to Gene Order
Share to Genes, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Essential

Share to Microbial Viability

Share to Mutation

Share to Operon

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 22768221
DOI: 10.1371/journal.pone.0040064
PMCID: PMC3386938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High confidence prediction of essential genes in Burkholderia cenocepacia.PMID 22768221Read ↗

In Silico Analysis of Burkholderia pseudomallei Genome Sequence for Potential Drug TargetsSemantic proximity Read ↗

The Essential Genome of Burkholderia cenocepacia H111.Semantic proximity Read ↗

Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDISSemantic proximity Read ↗

Essential Bacillus subtilis genes.Semantic proximity Read ↗

Identification of Essential Operons with a Rhamnose-Inducible Promoter in Burkholderia cenocepaciaSemantic proximity Read ↗

Identification of Essential Protein Domains From High-density Transposon Insertion SequencingSemantic proximity Read ↗

In Vivo -Validated Essential Genes Identified in Acinetobacter baumannii by Using Human Ascites Overlap Poorly with Essential Genes Detected on Laboratory MediaSemantic proximity Read ↗

Predicting conserved essential genes in bacteria: in silico identification of putative drug targets.Semantic proximity Read ↗

Combining Functional and Structural Genomics to Sample the Essential Burkholderia StructomeSemantic proximity Read ↗

CEG 2.0: an updated database of clusters of essential genes including eukaryotic organismsSemantic proximity Read ↗

Genome-Wide Saturation Mutagenesis of Burkholderia pseudomallei K96243 Predicts Essential Genes and Novel Targets for Antimicrobial DevelopmentSemantic proximity Read ↗

Genome-wide essential gene identification in Streptococcus sanguinis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.