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Article

Unified Sequence-Based Association Tests Allowing for Multiple Functional Annotations and Meta-analysis of Noncoding Variation in Metabochip Data.

American journal of human genetics - 7 Sept 2017

He Zihuai, Xu Bin, Lee Seunggeun, Ionita-Laza Iuliana

Abstract excerpt

Substantial progress has been made in the functional annotation of genetic variation in the human genome. Integrative analysis that incorporates such functional annotations into sequencing studies can aid the discovery of disease-associated genetic variants, especially those with unknown function and located outside protein-coding regions. Direct incorporation of one functional annotation as weight in existing...

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Identifiers

PMID: 28844485
DOI: 10.1016/j.ajhg.2017.07.011
PMCID: PMC5590864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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