Article
Phosphorylation of Lbx1 controls lateral myoblast migration into the limb.
Developmental biology - 15 Oct 2017
Masselink Wouter, Masaki Megumi, Sieiro Daniel, Marcelle Christophe, Currie Peter D
Abstract excerpt
The migration of limb myogenic precursors from limb level somites to their ultimate site of differentiation in the limb is a paradigmatic example of a set of dynamic and orchestrated migratory cell behaviours. The homeobox containing transcription factor ladybird homeobox 1 (Lbx1) is a central regulator of limb myoblast migration, null mutations of Lbx1 result in severe disruptions to limb muscle formation,...
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