Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndrome

27 Aug 2010

Abstract excerpt

To identify cytogenetic risk factors predicting outcome in children with advanced myelodysplastic syndrome, overall survival of 192 children prospectively enrolled in European Working Group of Myelodysplastic Syndrome in Childhood studies was evaluated with regard to karyotypic complexity. Structurally complex constitutes a new definition of complex karyotype characterized by more than or equal to 3 chromosomal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Retinoids in leukemia and cellular processes
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20802024
DOI: 10.1182/blood-2010-04-280313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndromePMID 20802024Read ↗

Complex, Not Monosomal, Karyotype Is the Cytogenetic Marker of Poorest Prognosis in Patients With Primary Myelodysplastic SyndromeSemantic proximity Read ↗

Monosomal karyotype predicts inferior survival independently of a complex karyotype in patients with myelodysplastic syndromesSemantic proximity Read ↗

Molecular cytogenetic profiling of complex karyotypes in primary myelodysplastic syndromes and acute myeloid leukemiaSemantic proximity Read ↗

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.Semantic proximity Read ↗

New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patientsSemantic proximity Read ↗

Monosomal karyotype in myelodysplastic syndromes, with or without monosomy 7 or 5, is prognostically worse than an otherwise complex karyotypeSemantic proximity Read ↗

Cytogenetic features in myelodysplastic syndromesSemantic proximity Read ↗

Monosomal karyotype in primary myelofibrosis is detrimental to both overall and leukemia-free survivalSemantic proximity Read ↗

TP53 mutations are associated with very complex karyotype and suggest poor prognosis in newly diagnosed myelodysplastic syndrome patients with monosomal karyotype.Semantic proximity Read ↗

Clinical significance of cytogenetic and molecular genetic abnormalities in 634 Chinese patients with myelodysplastic syndromes.Semantic proximity Read ↗

[Clinical features and prognostic factors of advanced myelodysplastic syndromes in children].Semantic proximity Read ↗

Prognostic value of monosomal karyotype in comparison to complex aberrant karyotype in acute myeloid leukemia: a study on 824 cases with aberrant karyotypeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.