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Epigenetic changes by DNA methylation in chronic and intermittent hypoxia

25 Aug 2017

Abstract excerpt

DNA methylation of cytosine residues is a well-studied epigenetic change, which regulates gene transcription by altering accessibility for transcription factors. Hypoxia is a pervasive stimulus that affects many physiological processes. The circulatory and respiratory systems adapt to chronic sustained hypoxia, such as that encountered during a high-altitude sojourn. Many people living at sea level experience...

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PMID: 28839104
DOI: 10.1152/ajplung.00325.2017

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