Article
Telomere length in hepatocellular carcinoma and paired adjacent non-tumor tissues by quantitative PCR.
Cancer investigation - 1 Dec 2007
Zhang Yujing, Shen Jing, Ming-Whei, Lee Yu Po-Huang, Santella Regina M
Abstract excerpt
Telomere shortening limits the proliferative capacity of human cells, restrains the regenerative capacity of organ systems during chronic diseases and aging and also induces chromosomal instability as well as initiation of cancer. Previous studies demonstrated that telomeres are often significantly shorter in tumor tissue, including hepatocellular carcinoma (HCC), compared to the surrounding tissue, but telomere...
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