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BRCA1/2gene mutations do not affect the capacity of oocytes from breast cancer candidates for fertility preservation to maturein vitro

7 Dec 2018

Abstract excerpt

STUDY QUESTION: Are the maturation rates of oocytes recovered from small antral follicles different between breast cancer patients presenting with or without a BRCA 1/2 gene mutation? SUMMARY ANSWER: BRCA 1/2 gene mutations do not affect the capacity of oocytes from breast cancer candidates for fertility preservation to mature in vitro. WHAT IS KNOWN ALREADY: Mutations in the BRCA1 and BRCA2 genes are associated...

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PMID: 30561604
DOI: 10.1093/humrep/dey358

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