Article
Capsule Type and Amount Affect Shedding and Transmission of Streptococcus pneumoniae.
mBio - 22 Aug 2017
Zafar M Ammar, Hamaguchi Shigeto, Zangari Tonia, Cammer Michael, Weiser Jeffrey N
Abstract excerpt
The capsular polysaccharide (CPS) of Streptococcus pneumoniae is characterized by its diversity, as it has over 95 known serotypes, and the variation in its thickness as it surrounds an organism. While within-host effects of CPS have been studied in detail, there is no information about its contribution to host-to-host transmission. In this study, we used an infant mouse model of intralitter transmission,...
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