Article
Ultradeep sequencing of B and non-B HIV-1 subtypes: Viral diversity and drug resistance mutations before and after one month of antiretroviral therapy in naive patients.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Oct 2017
Epaulard Olivier, Signori-Schmuck Anne, Larrat Sylvie, Kulkarni Om, Blum Michael G, Fusillier Katia, Blanc Myriam, Leclercq Pascale, François Olivier, Morand Patrice
Abstract excerpt
BACKGROUND: Ultradeep pyrosequencing technologies permit an assessment of the genetic diversity and the presence and frequency of minority variants in a viral population. The effect of these parameters on the outcome of highly active antiretroviral therapy (HAART) in HIV-infected patients is poorly understood. OBJECTIVES: The present study used the pyrosequencing Roche 454 prototype assay to determine whether...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.