Article
Discovering potential driver genes through an integrated model of somatic mutation profiles and gene functional information.
Molecular bioSystems - 26 Sept 2017
Xi Jianing, Wang Minghui, Li Ao
Abstract excerpt
The accumulating availability of next-generation sequencing data offers an opportunity to pinpoint driver genes that are causally implicated in oncogenesis through computational models. Despite previous efforts made regarding this challenging problem, there is still room for improvement in the driver gene identification accuracy. In this paper, we propose a novel integrated approach called IntDriver for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
