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Article

Impairment of PTX3 expression in osteoblasts: a key element for osteoporosis

12 Oct 2017

Abstract excerpt

Pentraxin 3 (PTX3) is a multifunctional glycoprotein regulating inflammatory response, cell proliferation and migration and deposition and remodelling of the extracellular matrix by a variety of cells. In this study, we investigated the possible role of PTX3 in bone homeostasis. To this end, we compared the expression and function of PTX3 in human osteoblasts of osteoporotic, osteoarthritic patients and young...

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PMID: 29022895
DOI: 10.1038/cddis.2017.514

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