Risk Factors and Outcomes of Thalidomide-induced Peripheral Neuropathy in a Pediatric Inflammatory Bowel Disease Cohort.

doi:10.1097/MIB.0000000000001195

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Risk Factors and Outcomes of Thalidomide-induced Peripheral Neuropathy in a Pediatric Inflammatory Bowel Disease Cohort.

Inflammatory bowel diseases - 1 Oct 2017

Bramuzzo Matteo, Stocco Gabriele, Montico Marcella, Arrigo Serena, Calvi Angela, Lanteri Paola, Costa Stefano, Pellegrino Salvatore, Magazzù Giuseppe, Barp Jacopo, Ghione Silvia, Lionetti Paolo, Zuin Giovanna, Fontana Massimo, Di Chio Teresa, Maggiore Giuseppe, Lazzerini Marzia, Lucafò Marianna, Udina Chiara, Pellegrin Maria Chiara, Chicco Andrea, Carrozzi Marco, Decorti Giuliana, Ventura Alessandro, Martelossi Stefano

Abstract excerpt

BACKGROUND: Thalidomide is an effective therapy in children with inflammatory bowel disease refractory to standard treatments, but thalidomide-induced peripheral neuropathy (TiPN) limits its long-term use. We aimed to investigate the risk factors and the outcome of TiPN in children with inflammatory bowel disease. METHODS: Within a retrospective multicenter cohort study, we evaluated prevalence and evolution of...

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PMID: 28817461
DOI: 10.1097/MIB.0000000000001195

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