Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptome Profiling Reveals B-Lineage Cells Contribute to the Poor Prognosis and Metastasis of Clear Cell Renal Cell Carcinoma

12 Aug 2021

Abstract excerpt

Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) significantly, there are still a large proportion of ccRCC patients who progress to metastasis. Targeting the pro-metastatic immune cell in the ccRCC microenvironment could provide a solution to this problem. In this study, B cells in ccRCC biopsies were identified by using scRNA-seq and flow cytometry. The findings...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Renal and related cancers
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34485161
DOI: 10.3389/fonc.2021.731896

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptome Profiling Reveals B-Lineage Cells Contribute to the Poor Prognosis and Metastasis of Clear Cell Renal Cell CarcinomaPMID 34485161Read ↗

Deciphering Tumor Metastasis and Immune Inhibitory Signature of Clear Cell Renal Cell Carcinoma by Single-Cell Transcriptome AnalysisSemantic proximity Read ↗

Transcriptomic characterization and innovative molecular classification of clear cell renal cell carcinoma in the Chinese populationSemantic proximity Read ↗

Tumor microenvironment immune subtypes for classification of novel clear cell renal cell carcinoma profiles with prognostic and therapeutic implications.Semantic proximity Read ↗

Immune Phenotype-Genotype Associations in Primary Clear Cell Renal Cell Carcinoma and Matched Metastatic Tissue.Semantic proximity Read ↗

Exploration of the relationships between tumor mutation burden with immune infiltrates in clear cell renal cell carcinomaSemantic proximity Read ↗

Identification of a Metastasis-Associated Gene Signature of Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

Analyzing and validating the prognostic value and immune microenvironment of clear cell renal cell carcinomaSemantic proximity Read ↗

Significance of Tumor Mutation Burden Related Immune Gene in the Progression and Prognosis of Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

Basement membrane genes can predict the prognosis of patients with clear cell renal cell carcinoma (ccRCC) and are correlated with immune statusSemantic proximity Read ↗

The immune reprogramming mediated by MZB1 reveals the immune and prognostic features of clear cell renal cell carcinomaSemantic proximity Read ↗

N6-methyladenosine Methylation Related Immune Biomarkers Correlates With Clinicopathological Characteristics and Prognosis in Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

The Prognosis-related Genes Participate in Immunotherapy of Renal Clear Cell Carcinoma Maybe Through Targeting Dendritic CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.