Article
Circulating levels of soluble Fas (sCD95) are associated with risk for development of a nonresolving acute kidney injury subphenotype.
Critical care (London, England) - 17 Aug 2017
Bhatraju Pavan K, Robinson-Cohen Cassianne, Mikacenic Carmen, Harju-Baker Susanna, Dmyterko Victoria, Slivinski Natalie S J, Liles W Conrad, Himmelfarb Jonathan, Heckbert Susan R, Wurfel Mark M
Abstract excerpt
BACKGROUND: Critically ill patients with acute kidney injury (AKI) can be divided into two subphenotypes, resolving or nonresolving, on the basis of the trajectory of serum creatinine. It is unknown if the biology underlying these two AKI recovery patterns is different. METHODS: We measured eight circulating biomarkers in plasma obtained from a cohort of patients admitted to an intensive care unit (ICU)...
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