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Article

SLCO1B1 521T > C polymorphism associated with rosuvastatin-induced myotoxicity in Chinese coronary artery disease patients: a nested case-control study.

European journal of clinical pharmacology - 1 Nov 2017

Liu Ju-E, Liu Xiao-Ying, Chen Sheng, Zhang Yan, Cai Li-Yun, Yang Min, Lai Wei-Hua, Ren Bin, Zhong Shi-Long

Abstract excerpt

PURPOSE: This nested case-control study aimed to evaluate the association of candidate genetic variants with statin-induced myotoxicity in Chinese patients with coronary artery disease (CAD). METHODS: One hundred forty-eight Chinese patients experiencing statin-induced myotoxicity were included in our study, and 255 patients without muscular side effects served as controls. Five SNPs in CYP3A5, SLCO1B1, and APOE...

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Source

Identifiers

PMID: 28812116
DOI: 10.1007/s00228-017-2318-z

Genes

APOE
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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