Article
Transcriptomics and methylomics in chronic periodontitis with tobacco use: a pilot study.
Clinical epigenetics - 1 Jan 2017
Cho Young-Dan, Kim Pil-Jong, Kim Hong-Gee, Seol Yang-Jo, Lee Yong-Moo, Ku Young, Rhyu In-Chul, Ryoo Hyun-Mo
Abstract excerpt
BACKGROUND: Accumulating evidence suggests that tobacco smoking affects the susceptibility to and severity of chronic periodontitis. Epigenetics may explain the role of smoking in the development and progress of periodontal disease. In this study, we performed transcriptomic and methylomic analyses of non-periodontitis and periodontitis-affected gingival tissues according to smoking status. METHODS: Human...
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