Article
Gingival tissue transcriptomes identify distinct periodontitis phenotypes.
Journal of dental research - 1 May 2014
Kebschull M, Demmer R T, Grün B, Guarnieri P, Pavlidis P, Papapanou P N
Abstract excerpt
The currently recognized principal forms of periodontitis-chronic and aggressive-lack an unequivocal, pathobiology-based foundation. We explored whether gingival tissue transcriptomes can serve as the basis for an alternative classification of periodontitis. We used cross-sectional whole-genome gene expression data from 241 gingival tissue biopsies obtained from sites with periodontal pathology in 120...
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