Article

The role of Wiskott-Aldrich Syndrome protein in activation and function of human T cells

2006-01-01

Abstract excerpt

Wiskott-Aldrich Syndrome (WAS) is a X-linked genetic disease caused by mutation in the gene encoding for the Wiskott-Aldrich Syndrome protein (WASP). WASP is specifically expressed in hematopoietic cells, where it regulates the reorganization of actin cytoskeleton in response to extracellular stimuli. WAS is characterized by micro-throm bocytopenia, eczema, immunodeficiency and high susceptibility to autoimmune di...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 15032511-8d42-5a8f-ae45-2f0d5d512134
DOI: 10.21954/ou.ro.0000fafc

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The role of Wiskott-Aldrich Syndrome protein in activation and function of human T cellsDOI 10.21954/ou.ro.0000fafcRead

Wiskott–Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activationSemantic proximity Read

Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome.Semantic proximity Read

Wiskott-Aldrich syndrome: a comprehensive review.Semantic proximity Read

Wiskott‐Aldrich syndrome protein: Emerging mechanisms in immunitySemantic proximity Read

[Wiskott-Aldrich Syndrome: An updated review].Semantic proximity Read

WASP (Wiskott-Aldrich syndrome protein) gene mutations and phenotype.Semantic proximity Read

The Wiskott–Aldrich syndromeSemantic proximity Read

Autoimmunity in Wiskott–Aldrich Syndrome: An Unsolved EnigmaSemantic proximity Read

New insights into the biology of Wiskott-Aldrich syndrome (WAS).Semantic proximity Read

Clinical spectrum, pathophysiology and treatment of the Wiskott–Aldrich syndromeSemantic proximity Read

Wiskott–Aldrich Syndrome at the nexus of autoimmune and primary immunodeficiency diseasesSemantic proximity Read

Clinical Manifestations and Pathophysiological Mechanisms of the Wiskott-Aldrich Syndrome.Semantic proximity Read