Article
The nucleoid protein Dps binds genomic DNA of Escherichia coli in a non-random manner.
PloS one - 1 Jan 2017
Antipov S S, Tutukina M N, Preobrazhenskaya E V, Kondrashov F A, Patrushev M V, Toshchakov S V, Dominova I, Shvyreva U S, Vrublevskaya V V, Morenkov O S, Sukharicheva N A, Panyukov V V, Ozoline O N
Abstract excerpt
Dps is a multifunctional homododecameric protein that oxidizes Fe2+ ions accumulating them in the form of Fe2O3 within its protein cavity, interacts with DNA tightly condensing bacterial nucleoid upon starvation and performs some other functions. During the last two decades from discovery of this protein, its ferroxidase activity became rather well studied, but the mechanism of Dps interaction with DNA still...
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