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Article

A novel DNA-binding protein with regulatory and protective roles in starved Escherichia coli.

Genes & development - 1 Dec 1992

Almirón M, Link A J, Furlong D, Kolter R

Abstract excerpt

A starvation-inducible DNA-binding protein was discovered as a result of the analysis of proteins synthesized in 3-day-old cultures of Escherichia coli. This 19-kD protein, designated Dps, is abundant in starved cells. In vitro, Dps forms extremely stable complexes with DNA, without apparent sequence specificity. When complexed with Dps, DNA is rendered DNase resistant. Mutant cells lacking Dps show dramatic...

Topics

Amino Acid Sequence
Bacterial Proteins
DNA, Bacterial
DNA, Superhelical
DNA-Binding Proteins
Electrophoresis, Gel, Two-Dimensional
Electrophoresis, Polyacrylamide Gel
Escherichia coli
Hydrogen Peroxide
Kinetics
Microscopy, Electron

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Phenotype

Source

Identifiers

PMID: 1340475
DOI: 10.1101/gad.6.12b.2646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1340475-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A novel DNA-binding protein with regulatory and protective roles in starved Escherichia coli.PMID 1340475Read ↗

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