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Article

Mesenchymal stromal cells contribute to quiescence of therapy-resistant leukemic cells in acute myeloid leukemia.

European journal of haematology - 1 Nov 2017

Wang Wenwen, Bochtler Tilmann, Wuchter Patrick, Manta Linda, He Haiju, Eckstein Volker, Ho Anthony D, Lutz Christoph

Abstract excerpt

OBJECTIVE: Persistence of leukemic cells after induction therapy has been shown to correlate with poor survival in acute myeloid leukemia (AML). In this study, we tested if human mesenchymal stromal cells (hMSCs) have protective effects on leukemic cells undergoing chemotherapy. METHODS: Persistent disease was used as marker to identify cases with therapy-resistant leukemic cells in 95 patients with AML....

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Identifiers

PMID: 28800175
DOI: 10.1111/ejh.12934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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