Article
Vitamin D receptor gene FokI polymorphism in Egyptian children and adolescents with SLE: A case-control study.
Lupus - 1 Nov 2017
Imam A A, Ibrahim H E, Farghaly M A A, Alkholy U M, Gawish H H, Abdalmonem N, Sherif A M, Ali Y F, Hamed M E, Waked N M, Fathy M M, Khalil A M, Noah M A, Hegab M S, Ibrahim B R, Nabil R M, Fattah L A
Abstract excerpt
Background Childhood-onset systemic lupus erythematosus (cSLE) is a lifelong autoimmune disorder. The vitamin D receptor (VDR) gene is a potential candidate gene for cSLE susceptibility. In this study, we aimed to investigate the FokI polymorphism in the VDR gene in Egyptian children and adolescents with SLE, to determine whether this polymorphism could be a genetic marker for cSLE susceptibility or disease...
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