Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Identification of key targets for ergothioneine biosynthesis based on random genomic transposition and high-throughput screening].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 25 Sept 2026

Tang Weijie, Zhao Yiming, Tao Zun, Cai Bohan, Zhang Yuan, Wang Longtao, Wu Mengping, Zhou Guangzhen, Wu Jing, Liu Zhanzhi

Abstract excerpt

Ergothioneine (ERG), as a natural potent antioxidant, possesses excellent physicochemical properties and diverse physiological activities, thereby exhibiting broad application prospects. However, engineering of existing genetically modified strains is prone to encountering bottlenecks in yield improvement. To identify key regulatory genes involved in ERG biosynthesis and enhance its heterologous production...

Read the complete abstract on PubMed

Topics

Ergothioneine
Escherichia coli
High-Throughput Screening Assays
Metabolic Engineering
Fermentation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Hypocreales

Mutation

Source

Identifiers

PMID: 42773657
DOI: 10.13345/j.cjb.260048

Genes

ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Identification of key targets for ergothioneine biosynthesis based on random genomic transposition and high-throughput screening].PMID 42773657Read ↗

Engineering Mycolicibacterium neoaurum for the production of antioxidant ergothioneineSemantic proximity Read ↗

Engineering the yeast <i>Saccharomyces cerevisiae</i> for the production of L-(+)-ergothioneineSemantic proximity Read ↗

The discovery of ergothioneine biosynthesis genes from Pleurotus eryngii and its combinatorial expression in yeastSemantic proximity Read ↗

Role of Ergothioneine in Microbial Physiology and PathogenesisSemantic proximity Read ↗

Structural basis of ergothioneine biosynthesisSemantic proximity Read ↗

The Neurospora crassa mutant NcΔEgt-1 identifies an ergothioneine biosynthetic gene and demonstrates that ergothioneine enhances conidial survival and protects against peroxide toxicity during conidial germination.Semantic proximity Read ↗

The proteobacterial species <i>Burkholderia pseudomallei</i> produces ergothioneine, which enhances virulence in mammalian infectionSemantic proximity Read ↗

Engineering Saccharomyces boulardii for Probiotic Supplementation of l ‐ErgothioneineSemantic proximity Read ↗

Discovery and structure of a widespread bacterial ABC transporter specific for ergothioneineSemantic proximity Read ↗

Tn5 Transposon-based Mutagenesis for Engineering Phage-resistant Strains of Escherichia coli BL21 (DE3).Semantic proximity Read ↗

Discovery and structure of a widespread bacterial ABC transporter specific for ergothioneineSemantic proximity Read ↗

A <i>Trypanosoma brucei</i> ORFeome-based Gain-of-Function Library reveals novel genes associated with melarsoprol resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.