Article
Early transition from insulin to sulfonylureas in neonatal diabetes and follow-up: Experience from China.
Pediatric diabetes - 1 Mar 2018
Li Xiuzhen, Xu Aijing, Sheng Huiying, Ting Tzer Hwu, Mao Xiaojian, Huang Xinjiang, Jiang Minyan, Cheng Jing, Liu Li
Abstract excerpt
BACKGROUND: Sulfonylurea therapy can improve glycemic control and ameliorate neurodevelopmental outcomes in patients suffering from neonatal diabetes mellitus (NDM) with KCNJ11 or ABCC8 mutations. As genetic testing results are often delayed, it remains controversial whether sulfonylurea treatment should be attempted immediately at diagnosis or doctors should await genetic confirmation. OBJECTIVE: This study...
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