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Article

Sulfonylurea in the treatment of neonatal diabetes mellitus children with heterogeneous genetic backgrounds.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Jul 2015

Zhang Miaoying, Chen Xiuli, Shen Shuixian, Li Tang, Chen Linqi, Hu Min, Cao Lingfeng, Cheng Ruoqian, Zhao Zhuhui, Luo Feihong

Abstract excerpt

OBJECTIVE: The pathogenic base of neonatal diabetes mellitus (NDM) is highly heterogeneous. Sulfonylurea (SU) has been successfully applied in majority of NDM patients with KATP channel mutations; however, its rationality and effectiveness among patients with NDM stemmed from other genetic mutations have not been established. The objective of the present study was to investigate the effectiveness of SU therapy in...

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Share to Blood Glucose
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Background

Share to Hypoglycemic Agents

Share to Infant, Newborn, Diseases

Share to Potassium Channels, Inwardly Rectifying

Share to Sulfonylurea Compounds

Share to Sulfonylurea Receptors

Source

Identifiers

PMID: 25781672
DOI: 10.1515/jpem-2014-0429

Genes

INS
ABCC8
KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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