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Article

Improved long-term glucose control in neonatal diabetes mellitus after early sulfonylurea allergy.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Jan 2012

Shah Bina, Breidbart Emily, Pawelczak Melissa, Lam Leslie, Kessler Marion, Franklin Bonita

Abstract excerpt

BACKGROUND: Activating mutations of the ABCC8 gene can lead to permanent neonatal diabetes mellitus (PNDM). Glucose variability in infants with NDM treated with insulin can be extreme. We report long-term glycemic control in a patient with PNDM on sulfonylurea therapy, despite initial allergic reaction. METHODS: A Chinese girl presented on the first day of life with persistent hyperglycemia. Despite treatment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glycated Hemoglobin

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Share to Potassium Channels, Inwardly Rectifying

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Source

Identifiers

PMID: 22768668
DOI: 10.1515/jpem-2011-0449

Genes

ABCC8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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