Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Efficacy and safety of sulfonylurea use in permanent neonatal diabetes due to KCNJ11 gene mutations: 34-month median follow-up.

Diabetes technology & therapeutics - 1 May 2010

Klupa Tomasz, Skupien Jan, Mirkiewicz-Sieradzka Barbara, Gach Agnieszka, Noczynska Anna, Zubkiewicz-Kucharska Agnieszka, Szalecki Mieczyslaw, Kozek Elzbieta, Nazim Joanna, Mlynarski Wojciech, Malecki Maciej T

Abstract excerpt

BACKGROUND: Recently, many patients with Kir6.2-related permanent neonatal diabetes mellitus (PNDM) have been successfully transferred from insulin therapy to sulfonylurea (SU) treatment. The long-term efficacy and safety of SU treatment in PNDM patients, however, have not yet been determined. ME...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Glycated Hemoglobin

Share to Hypoglycemic Agents

Share to Potassium Channels, Inwardly Rectifying

Share to Sulfonylurea Compounds

Share to Treatment Outcome

Source

Identifiers

PMID: 20184447
DOI: 10.1089/dia.2009.0165

Genes

KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20184447-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Efficacy and safety of sulfonylurea use in permanent neonatal diabetes due to KCNJ11 gene mutations: 34-month median follow-up.PMID 20184447Read ↗

Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study.Semantic proximity Read ↗

Sulfonylurea vs insulin therapy in individuals with sulfonylurea-sensitive permanent neonatal diabetes mellitus, attributable to a KCNJ11 mutation, and poor glycaemic control.Semantic proximity Read ↗

Permanent neonatal diabetes by a new mutation in KCNJ11: unsuccessful switch to sulfonylurea.Semantic proximity Read ↗

Long-term Follow-up of Glycemic and Neurological Outcomes in an International Series of Patients With Sulfonylurea-Treated ABCC8 Permanent Neonatal Diabetes.Semantic proximity Read ↗

Early transition from insulin to sulfonylureas in neonatal diabetes and follow-up: Experience from China.Semantic proximity Read ↗

Prevalence of permanent neonatal diabetes in Slovakia and successful replacement of insulin with sulfonylurea therapy in KCNJ11 and ABCC8 mutation carriers.Semantic proximity Read ↗

Mother and daughter carrying the same KCNJ11 mutation but with a different response to switching from insulin to sulfonylurea.Semantic proximity Read ↗

Permanent neonatal diabetes mellitus: same mutation, different glycemic control with sulfonylurea therapy on long-term follow-up.Semantic proximity Read ↗

Permanent neonatal diabetes mellitus due to KCNJ11 mutation in a Portuguese family: transition from insulin to oral sulfonylureas.Semantic proximity Read ↗

Comparison of diabetes phenotype in children and their mothers with permanent neonatal diabetes mellitus carrying the same KCNJ11 variants.Semantic proximity Read ↗

Successful transfer from insulin to oral sulfonylurea in a 3-year-old girl with a mutation in the KCNJ11 gene.Semantic proximity Read ↗

Sulfonylurea treatment outweighs insulin therapy in short-term metabolic control of patients with permanent neonatal diabetes mellitus due to activating mutations of the KCNJ11 (KIR6.2) geneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.