Article
CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia.
Circulation. Cardiovascular genetics - 1 Aug 2017
Siddiqui Moneeza Kalhan, Veluchamy Abirami, Maroteau Cyrielle, Tavendale Roger, Carr Fiona, Pearson Ewan, Colhoun Helen, Morris Andrew D, George Jacob, Doney Alexander, Pirmohamed Munir, Alfirevic Ana, Wadelius Mia, Maitland van der Zee Anke H, Ridker Paul M, Chasman Daniel I, Palmer Colin N A
Abstract excerpt
BACKGROUND: To test the association of a recently reported variant in the creatine kinase (CK) muscle gene, CKM Glu83Gly (rs11559024) with constitutive creatine phosphokinase (CK) levels, CK variation, and inducibility. Given the diagnostic importance of CK in determining muscle damage, we tested the association of the variant with myalgia. METHODS AND RESULTS: Meta-analysis between longitudinal cohort GoDARTS...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.