Article
Mutation that affects pepN translation initiation in Escherichia coli.
Biochimie - 1 Jan 2000
Gharbi S, Bally M, Lazdunski A, Murgier M
Abstract excerpt
Mutants altered in their expression of the hybrid pepN-lacZ gene have been selected for resistance to p-nitrophenyl-beta-D-thiogalactopyranoside (a bacteriostatic compound that enters the cells via lac permease). A unique mutation decreasing the level of pepN expression to 9% of that of the wild...
Topics
- Aminopeptidases
- Bacteriophage lambda
- Base Sequence
- CD13 Antigens
- Cloning, Molecular
- Codon
- DNA, Bacterial
- DNA, Recombinant
- Drug Resistance, Microbial
- Escherichia coli
- Genes, Bacterial
- Mutation
- Nucleic Acid Conformation
- Peptide Chain Initiation, Translational
- Thiogalactosides
